Gluten-Reactivity is a systemic autoimmune disease with many different manifestations. What is autoimmunity? It is a condition in which your own body is attacking itself with its own Immune (defense) system. Celiac disease or gluten sensitive enteropathy (gastro-intestinal disease) is only one, of a range of possible manifestations of reactivity to gluten. Celiacs disease, because it is the most commonly known manifestations of Gluten-Reactivity, receives the most attention to the point of ignoring all the other manifestations that can arise. Autoimmune disease is the third leading cause of death in the industrialized world, which includes diseases such as; Crohn’s, Diabetes I, Hypo/Hyper Thyroidism and SLE to name a few. Autoimmune disease is 10 times more common in a person with Gluten-Reacivity compared to the general population. So we can see that the burden on our society from Gluten-Reactivity cannot be overlooked. Early identification of this plaguing condition can result in earlier treatment, better quality of life and an improved prognosis.